Another study demonstrated that dietary Trp deficiency triggered dysbiosis, depletion of kynurenines and other amino acid-related metabolites, leading to upregulation of RAR-related orphan receptor-γ+ (RORγt) Tregs over GATA binding protein 3+ (GATA3) Tregs, with RORγt+ Tregs being linked to bacterial infection. Here, GATA3 is linked to bacterial infectious disease.