CCNE1 and early-onset autosomal dominant Alzheimer disease: Aberrant cell cycle reentry or cell cycle arrest was reflected by increased expression levels of Ki67, proliferating cell nuclear antigen, cyclin E and cyclin D1 in the muscle samples from the patients with inclusion body myositis and polymyositis, as well as the brain samples from Alzheimer’s disease patients (Kwon et al., 2014).