However, upon analyzing correlations among nondiabetic individuals with or without obesity (NOND-OND), diabetic individuals with or without obesity (NOD-OD), and obese diabetics (NOND-OD), the findings align with those observed in gerbils, only negative correlations between adiponectin and leptin, and positive correlations between adiponectin and HDL. This evidence concerns the gene LEP and obesity due to melanocortin 4 receptor deficiency.