TP53 and ependymoma: The markers available include S100, GFAP, ATRX, olig-2, EMA, enolase, neurofilament, IDH1, p53, and IN1-1, but most countries with immunohistochemistry are still lacking stains such as GAB-1 necessary for proper classification of medulloblastoma and YAP-1 useful in both medulloblastomas and ependymomas, ZFTA which is used in the diagnosis of supratentorial ependymomas, and H3 K27 which is important in diffuse midline gliomas.