FGG and Venous thrombosis: However, since not all hypo(dys)fibrinogenemias are associated with venous thrombosis, as was also observed in a recently published study on CFD's (28), it is likely that other qualitative properties of fibrinogen conferred by the FGG p.Tyr375Cys mutation also contribute to a prothrombotic state, possibly by altering cloth strength, structure or stability (27).