CD40LG and primary biliary cholangitis: Thrombophilia testing was unremarkable, but autoimmune disease testing revealed the presence of anti-pyruvate DH IgG-M2 and anti-pyruvate DH (immunoglobulin (Ig)G, IgA, IgM) - M2 antibodies. She was referred to the Autoimmune Diseases Clinic in the Internal Medicine department at ULS Coimbra, and a probable diagnosis of primary biliary cholangitis (PBC) was made.