However, in immunocompromised individuals, such as acquired immunodeficiency syndrome (AIDS), the disease becomes severely symptomatic, especially when the cluster of differentiation 4 (CD4) count declines to less than 200 cells/mm3, moreover with a CD4 count of fewer than 50 cells/mm3 [2]. Toxoplasma encephalitis is an established complication in HIV patients, presented with a space-occupying lesion in the supratentorial area, usually manifesting as a focal neurological deficit [3,4]. The gene discussed is CD4; the disease is cerebral toxoplasmosis.