RS1 and cyst: At subsequent time points, 2 and 5 MPI, since cyst severity naturally decrease in untreated Rs1-KO eyes (Figure 1B), we did not observe significant differences in cyst severity among untreated, vector-treated, or hypertonic buffer-injected eyes (14) There is no notable change in ONL thickness from 1 to 5 MPI in all cohorts; however, at 5 MPI, vector treated eyes had a statistically thinner ONL than untreated eyes (p = 0.0341) (Figure 2C).