METTL3 and glioblastoma: In neurosphere assays of human glioblastoma cell lines, silencing METTL3 reduces the expression of glioblastoma reprogramming factors POU3F2, SOX2, SALL2, and OLIG2, and inhibits glioblastoma cell proliferation (Visvanathan et al., 2018; Chang et al., 2021a).