CYP2C19 and Hypertension: Multivariate regression logistic analysis showed that history of smoking (yes vs. no, OR: 1.193, 95% CI: 1.002–1.422, p = 0.048), hypertension (yes vs. no, OR: 3.371, 95% CI: 2.914–3.898, p < 0.001), diabetes mellitus (yes vs. no, OR: 1.911, 95% CI: 1.632–2.237, p < 0.001), CYP2C19 IM + PM phenotype (IM + PM phenotype vs. EM phenotype, OR: 1.424, 95% CI: 1.243–1.631, p < 0.001), and dyslipidemia (yes vs. no, OR: 1.294, 95% CI: 1.077–1.554, p = 0.006) were independent risk factors for premature CI (Table 4).