ESR1 and neoplasm: The multivariate logistic regression analysis shows that the demographic and clinicopathologic factors including age, family history, menopausal status, tumor site, and hormonal status of ER and PR had a non-significant impact as confounding factors (p = 0.601, p = 0.645, p = 0.233, p = 0.101, p = 0.694, p = 0.496, p = 0.541, respectively).