Additionally, Reactome enrichment analysis for the NC and SH groups showed associations with post-translational protein phosphorylation (Fig. 5E), while differential gene analysis between the SH and NIC groups in WikiPathways enrichment revealed relevance to FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma (Fig. 5F). This evidence concerns the gene KDM2B and diffuse large B-cell lymphoma.