P2RY1 and acute coronary syndrome: In the Treatment With ADP Receptor Inhibitors: Longitudinal Assessment of Treatment Patterns and Events After Acute Coronary Syndrome (TRANSLATE-ACS) registry, 28.3% of patients discharged on ticagrelor after PCI for MI switched to clopidogrel (87.5%) or prasugrel (12.5%) after a median of 50 days.14In contrast to our findings, the most cited reason for treatment alteration was socioeconomic (i.e., out-of-pocket costs).