ARID1A and hepatocellular carcinoma: It is the most frequently mutated subunit of the SWI/SNF complex, with inactivating mutations found in 6% of cancers, including ovarian clear cell cancers (45% of cases), uterine endometrioid cancers (37%) and hepatocellular carcinoma HCC (14%), highlighting the roles of ARID1A in cancer [16].