KCNT2 and diabetic neuropathy: However, when focusing specifically on participants with diabetic neuropathy, the GWAS on neuropathic pain intensity (n = 1541) identified a genome-wide significant association with a locus located on chromosome 1q31.3 (Fig. 2, rs114159097, P = 3.55 × 10−8) within the potassium sodium–activated channel subfamily T member 2 (KCNT2) gene.