Ou et al. (Ou et al. 2024) analyzed scRNA-seq data and weighted correlation network analysis (WGCNA) to reveal that M2 macrophage-associated genes (PLPP1, SMOC2, ABCG1, HES1, GPR160, MAZ, STMN1, EPCAM and MYC), and that M2 macrophages contribute to the proliferation, invasion and migration of PCa. The gene discussed is MYC; the disease is posterior cortical atrophy.