Wen et al. (Wen et al. 2023) analyzed the scRNA-seq data of PCa and found that HOPX, LY6E, THBS1, LDHA, CRISPLD2, FOXC1, SAMD4A, NR4A1, MYC and UBE2S were all involved in the occurrence of PCa. The gene discussed is UBE2S; the disease is posterior cortical atrophy.