IRAK1 and posterior cortical atrophy: Zhang et al. (Schagdarsurengin et al. 2022)found that IRAK1 is enriched in luminal epithelial cells and is regulated by the epigenetic state of the IRAK1 differentially methylated region (IRAK1-DMR) to exert an anti-apoptotic effect in luminal epithelial cells by using the analysis of scRNA-seq data in PCa.