Although mucinous tumours may also be challenging to detect on DWI (as mucin content typically does not result in restricted diffusion), they are typically well appreciated due to their high signal on T2-weighted MRI and low b-value DWI (as shown in the example of mucinous adenocarcinoma of the appendix in Fig. 3). Here, MUC5AC is linked to colon mucinous adenocarcinoma.