In the context of MS, the results noted a positive causal effect of four cytokines, including C‐X‐C motif chemokine 10 (OR = 1.2726, p = 0.0120), Leukaemia inhibitory factor receptor (OR = 1.1819, p = 0.0254), Natural killer cell receptor 2B4 (OR = 1.2092, p = 0.0192) and T‐cell surface glycoprotein CD6 isoform (OR = 1.1379, p = 0.0027), contrasted with a negative causal effect of three cytokines, namely Adenosine Deaminase (OR = 0.7675, p = 0.0024), CD40L receptor (OR = 0.7737, p = 1.1265E‐09) and Neurturin (OR = 0.7001, p = 0.0042) (Table S1—Data S1). Here, NRTN is linked to myeloid sarcoma.