It can regulate the proliferation, migration and apoptosis of vascular smooth muscle cells, and thereby influence the formation and progression of atherosclerosis.[29] Anxiety may affect the level of androgen and the activity of the AR signaling pathway, and thereby influence the incidence and prognosis of coronary heart disease.[30] The lipid and atherosclerosis pathway is involved in lipid metabolism and the formation of atherosclerosis, mainly related to cholesterol, triglyceride, apolipoprotein, and other factors. Here, AR is linked to Anxiety.