Previous studies have found that patients with sleep apnea have significantly increased PCSK9 levels and larger plasma low-density lipoprotein diameters after statin use.[8] According to Sanja Jelic, statins may be 1 way to improve the health of people with sleep apnea.[41] The study found that statins, but not CPAP (continuous positive airway pressure), protected blood vessels from dangerous inflammatory changes that occur in patients with sleep apnea. Here, PCSK9 is linked to Sleep apnea.