This underscores the intricate interplay between the immunocyte phenotypes and polymyositis, in which CD8, CD33dim, HLA-DR, CD11b, and CD45 may represent potential immune cell markers for polymyositis, paving the way for novel avenues of research into the biological mechanisms of polymyositis and facilitating disease prevention and early treatment. This evidence concerns the gene PTPRC and polymyositis.