AGT and triple-A syndrome: AAA formation was considered as a complex process and 3 mouse models have been used to study the pathological conditions of AAA: transient perfusion of elastase model, periaortic application with Cacl2 model and subcutaneous infusion of angiotensin II model.[19,32–34] These AAA-inducing models mainly depended on the mechanical injury to the arterial wall.[35] Different aortic pathologies were observed in these models.