Furthermore, MIBC with sarcomatoid/rhabdoid morphology, that are often Ba/Sq and known to exhibit strong epithelial to mesenchymal transition (EMT) activity and usually present with advanced pT-stage and increased metastatic incidence at the time of diagnosis (30–32), exhibited the highest HLA-G expression levels on tumor cells (Kruskal-Wallis test for multiple group comparisons: P=0.0003; Figure 2B). Here, HLA-G is linked to neoplasm.