The results of the meta-analysis indicated that the perioperative nutritional indicators of patients with gastric cancer undergoing surgery in the enteral nutrition with ω-3 polyunsaturated fatty acid preparation group were superior to those in the conventional EN preparation group, specifically for Total protein (WMD = 0.68, P = 0.05), Albumin (WMD = 0.34, P = 0.03), and Transferrin (WMD = 0.07, P = 0.03). The gene discussed is TF; the disease is gastric cancer.