In the T47D cell line, p21 was also decreased in the BYL-719 treated group (1 μM, 24 h) (p = 0.0237; 95% CI, 0.1697–1.378) and the STAT signaling pathway, which were associated with breast cancer and the stem cells (Figure 3E). This evidence concerns the gene CDKN1A and breast carcinoma.