For the other receptors studied, there was no correlation between substance-related RORs for the SMQ ‘drug-related hepatic disorders - comprehensive search’ and receptor-specific affinities or occupancies: dopamine receptors (D2, D3), serotonin receptors (5-HT2A, 5-HT2C and 5-HT7), histamine receptor (H1), adrenergic receptors (α1-adrenergic, α2-adrenergic. The gene discussed is HTR2C; the disease is liver disorder.