DisgeNET disease enrichment analysis (Figure 1B) disclosed several upregulated genes associated with Alzheimer’s disease (CSF1R, EPHB2, SERPINE1, PLPP4, COL4A4, LTBP2, IGFBP3, HHIP, DOCK2, CRISPLD2, DNER, ALOX5AP, NOX4, TGFBI, PROC, SMAD7, JUNB, ERG, and AMIGO2). This evidence concerns the gene JUNB and early-onset autosomal dominant Alzheimer disease.