HCRT and benign prostatic hyperplasia: A link between an overactive OX system and the pathophysiology of neurogenic hypertension has been established in spontaneously hypertensive rats (SHRs) and mice (BPH/2J) (Jackson et al., 2016; Lee et al., 2015; Lee et al., 2013; Li et al., 2013; Clifford et al., 2015).