Data are represented as mean ± SD. Student's independent t-test was used to compare the TC and LDL-C values between the different genotypes of LDLR-Ava II and APOB-Xba I genes in patients with severe hypercholesterolemia. A p-value of ≤0.05 was considered statistically significant (*). Here, APOB is linked to Hypercholesterolemia.