In the univariate analysis shown in Table 3, nephropathy, BUN, lactate dehydrogenase (LDH), creatinine level, total bilirubin, estimated glomerular filtration rate (eGFR), WBC count, lymphocyte count, albumin, CRP, interleukin-6 (IL-6), SAT, and PNI were associated with the death of critically ill patients with COVID-19. This evidence concerns the gene CRP and COVID-19.