Oxidative stress contributes to the development of coronary artery disease (6), lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1), of the scavenger receptors for oxidized low-density lipoprotein cholesterol (ox-LDL)- and superoxide dismutase-1 (SOD 1) being crucial components of the process. The gene discussed is SOD1; the disease is coronary artery disorder.