RAC2 and Alzheimer disease: Our transcriptomic data of lung tissue also showed downregulation of neutrophil extracellular trap formation (NET) pathway with downregulation of genes, such as Rac2, Elane, Padi4, and C5ar1 in animals treated with UC-MSCs, which was not evident in animals treated with AD-MSCs and BM-MSCs (Fig. 2a, Data S1).