PPARA and metabolic syndrome: Additionally, the green coffee potential bioactivity maintain physiological homeostasis, enhance physiological balance in MetS conditions and display cardio-protective through regulating lipid and glucose metabolism, IR, inflammation, modulation of adenosine monophosphate-activated protein kinase (AMPK) and Peroxisome Proliferator-Activated Receptor α (PPARα) gene expression in MetS rat model and mice [18–20].