TGFB1 can also deregulate various signaling pathways (NOTCH, WNT/β-catenin, PI3K/AKT, EGFR, RAS/RAF/MAPK) known to stimulate cell growth, survival and differentiation in other molecular subtypes of breast cancer (Figure S8; specifically, the activation of epidermal growth factor receptor, EGFR, expression in MCF7 cells is of interest; Fig. 5a). The gene discussed is AKT1; the disease is breast carcinoma.