Shahida Moosa et al. found that osteogenesis imperfecta (OI) is one of the disorders associated with LRP, and that variants in LRP5 and LRP6 lead to the development of different types of deformities and disorders such as fracture fragility or oligodontia (Moosa et al. 2019). Here, LRP5 is linked to osteogenesis imperfecta.