MECOM and cancer: Furthermore, the methylation status of PRDM2, PRDM5, PRDM6, PRDM8, PRDM9, PRDM10, PRDM12, PRDM13, PRDM14, and PRDM16 showed associations with cancer stage in UCEC, while no significant differences were observed in the promoter methylation of PRDM1, MECOM, PRDM4, PRDM7, PRDM11, and PRDM15 (Figure S6).