We conducted an analysis using the UALCAN server to investigate the potential role of promoter methylation in the downregulation of PRDM1, PRDM2, PRDM4, PRDM5, PRDM6, PRDM8, PRDM11, PRDM12, and PRDM16 mRNA expression in uterine corpus endometrial carcinoma (UCEC) tissues. The gene discussed is PRDM11; the disease is uterine corpus endometrial carcinoma.