MCIDAS and Hydrocephalus: To assess whether McIdas can induce direct reprogramming into ependyma in LPA-induced hydrocephalus, GFP-McIdas (McIdas) or GFP-expressing plasmids were electroporated onto P7 brains isolated from LPA-treated mice by targeting the dorsolateral wall of one lateral ventricle to introduce plasmids in cells located at periventricular regions.