TYMP and metastatic colorectal cancer: Trifluridine/thymidine phosphorylase inhibitor (FTD/TPI) is effective even in patients with metastatic colorectal cancer (mCRC) who are refractory to standard therapies, including fluoropyrimidine-, oxaliplatin-, and irinotecan-based chemotherapy, and is expected to further extend survival times in later-line therapy1.