When compared the top 20% of VEGFA expressing tumor samples to the bottom 20% expressing tumors and found that POLH goes up 1.69-fold (FDR 1 × 10−10), POLI goes up 2.06-fold (FDR 1.3 × 10−15) and REV3L goes up 1.62-fold (FDR 3.8 × 10−6; Supplementary Table S2). The gene discussed is POLH; the disease is neoplasm.