METTL3 and small cell lung carcinoma: In addition, the high expression of METTL3 in small cell lung cancer (SCLC) is associated with poor overall survival [104], while the reduced expression of METTL14 in OSCC correlates with advanced T stage, poor differentiation, and lymph node metastasis [38], suggesting that METTL14 is a biomarker of poor prognosis.