PTGDR and non-small cell lung carcinoma: In addition, research has also shown that m6A methylation modifications of AFAP1-AS1 promotes its translation into AFAP1-AS1 open reading frame 2 and inhibits the formation of autolysosomes by binding to the protein NIPSNAP1 on the inner mitochondrial membrane and trapping it, which is important for the malignant transformation of non-small cell lung cancer (NSCLC) cells [90].