To explore how 14-3-3ζ+++ cancer cell-secreted CXCL2/5 induce Cox2 expression in PSCs/fibroblasts, we profiled fibroblasts cultured in CM (10% FBS or 0% FBS) of Panc02.shCtrl cells or Panc02.shζ cells by RPPA. The gene discussed is PTGS2; the disease is cancer.