On day 3 postimplantation, an obvious increase in CRT expression and cytoplasmic translocation of nuclear HMGB1 was observed in the “APHP‐808”, “δ‐ALA+660”, and “CaCO3” groups (Figure 4F; Figure S6E,F, Supporting Information), indicating that PTT, PDT, and CIT can induce ICD in vivo. Here, HMGB1 is linked to impulse control disorder.