MICU1 and neoplasm: In contrast, we observed that TCGA-COAD tumor samples with a “high” status of MICU2 and the MICU2/MICU1 ratio present higher expression of genes associated with the assembly of complexes of the mitochondrial respiratory chain compared with tumor samples with a “low” status for MICU2 and the MICU2/MICU1 ratio (Figs 4B and S4B), suggesting that the expression of MICU2 may contribute to the assembly complexes or supercomplexes.