Papilloma formation in DMBA/TPA-treated K14CRE-ERT2-STIL+/- mice could not be rescued by concurrent expression of dominant-negative p53-R172H, a mutant p53 version that itself induces centrosome amplification, aneuploidy and skin tumor formation in a chemical skin carcinogenesis assay in mice [38]. The gene discussed is STIL; the disease is skin neoplasm.