Our findings showed that the expression level of Septin9 mRNA was higher in tumor tissues compared to normal tissues in various cancer types, such as COAD, BRCA, CHOL, ESCA, HNSC, KIRC, LUAD, LUSC, PRAD, STAD, THCA, and UCEC (Fig 2A, P<0.05). Here, SEPTIN9 is linked to cancer.