In the next study, we will carry on to enlarge the sample size for a multicenter trial and collect patients’ gene statuses of MSI, RAS, BRAF, PIK3CA, and Her2 to analyze the relationship between mSEPT9 and common mutated genes of bowel cancer, and to establish a diagnostic model for the surveillance of bowel cancer postoperative recurrence, with the aim of providing more bases for the selection of individualized postoperative treatment. Here, PIK3CA is linked to intestinal cancer.