In CECs we see many of the genes that have been found to altered in PAH and are not current targets for drugs, including the Wnt pathway (DKK1, DKK3), plurinucleate pathways (ENTPD1), and the inflammatory pathways (IL6, 7, 8, CXCL1). Here, ENTPD1 is linked to pulmonary arterial hypertension.