There is increasing awareness of the importance of chemerin in immune regulation and lipid biogenesis, which are biological processes associated with a number of common illnesses including acute inflammation, psoriasis, angiogenesis, obesity, diabetes, nonalcoholic fatty liver disease, ovarian cancer, and endometrial cancer [4–6,20]. The gene discussed is RARRES2; the disease is obesity due to melanocortin 4 receptor deficiency.