It was shown that stroke‐induced extrasynaptic glutamate release through neuronal BEST1 leads to delayed excitotoxicity in the mouse motor cortex19 and that cortical microglial cells enhance GABA uptake through the engagement of an interplay between the GABA transporter 1 (GAT‐1) and this channel upon a neuroinflammation insult.20 The gene discussed is SLC6A1; the disease is stroke disorder.