To evaluate the STING specificity of diABZI induced asthma exacerbation, response to the extracellularly released dsDNA, mice deficient for STING (STING−/−) or cGAS (cGAS−/−) were sensitized and challenged with HDM with or without diABZI as above (Figure 4A). This evidence concerns the gene CGAS and asthma.