Bronchial brushings from patients with asthma experimentally infected in vivo with RV‐A1631 (Figure 7E) showed a decrease in a group of tight junction‐related gene such as CLDN15, TJAP1, AKT2, SRC, CGN, EXOC3, LLG2, CLDN22, compared to similarly infected healthy controls, while CLDN12 and MYL12B genes were increased (Figure 7F). The gene discussed is CLDN22; the disease is asthma.