PYCARD and viral infectious disease: Moreover, analysis of PANoptosis related genes set revealed the upregulation and a tendency to upregulation of several components of the PANoptosome such as the pivotal ZBP1, PYCARD, CASPASE‐8, RIPK1, CASPASE‐1, and FADD after viral infection of the cells from patients with asthma compared to the controls (Figure 7D), which was not visible before RV infection (Figure E11 A–D—Figure S1).