To evaluate the STING specificity of diABZI induced asthma exacerbation, response to the extracellularly released dsDNA, mice deficient for STING (STING−/−) or cGAS (cGAS−/−) were sensitized and challenged with HDM with or without diABZI as above (Figure 4A). Here, STING1 is linked to asthma.