Numerous studies indicate that, alongside MMP and TIMP, several other inflammatory markers, including N-terminal pro-B-type natriuretic peptide (NT-proBNP), high-sensitive C-reactive protein (hsCRP), soluble suppression of tumorigenicity-2 (sST2), and high-sensitive troponin T (hs-TnT), have independent prognostic value in patients with congenital heart diseases [54–60]. The gene discussed is NPPB; the disease is congenital heart disease.